The **Thermal Cycler**, commonly known as a PCR machine, is a sophisticated laboratory instrument indispensable for molecular biology research. Our advanced systems facilitate the amplification of DNA segments through a process of thermal cycling, which involves precisely controlled temperature steps for denaturation, annealing, and extension. Equipped with high-performance Peltier heating and cooling blocks, our Thermal Cyclers ensure rapid temperature transitions and excellent uniformity across all wells. The touch-screen interface allows users to program complex protocols with ease, providing real-time monitoring of cycle progress. As a premier manufacturer, we offer Thermal Cyclers that are engineered for reliability and high-throughput performance, making them ideal for diagnostic laboratories, forensic science, and genetic engineering. Whether for gradient PCR or standard amplification, these units provide the thermal stability required for consistent and reproducible genetic results.
Thermal Cyclers are extensively applied in clinical diagnostics for identifying infectious diseases and genetic disorders. They are fundamental in forensic science for DNA profiling and paternity testing. In the pharmaceutical industry, they play a vital role in drug discovery and development. Furthermore, they are widely used in environmental biology to detect microbial pathogens in water and soil samples, as well as in agricultural biotechnology for GMO testing.
The significance of the Thermal Cycler lies in its ability to make billions of copies of a specific DNA sequence, allowing scientists to study small samples with high precision. Without this technology, modern genomics, COVID-19 testing, and personalized medicine would not be possible. It provides the essential thermal environment that ensures enzymes like Taq polymerase function correctly to replicate genetic material without errors.
This instrument is primarily used for Polymerase Chain Reaction (PCR) amplification. It is utilized for gene cloning, DNA sequencing preparation, and the study of gene expression. In research laboratories, it is used for site-directed mutagenesis and the detection of viral loads. Its adjustable ramp rates and gradient features also make it useful for optimizing the annealing temperatures of specific primers in complex biological assays.
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A gradient feature allows you to test different annealing temperatures across the block in a single run. This is crucial for optimizing new PCR protocols and primer sets efficiently.
Peltier technology allows for rapid heating and cooling (high ramp rates), which reduces the overall run time and ensures high thermal uniformity across all 96 wells.
Yes, our standard 96-well blocks are compatible with individual 0.2ml PCR tubes, 8-tube strips, and full 96-well non-skirted or semi-skirted plates.
Yes, our Thermal Cyclers feature an adjustable heated lid to apply the correct pressure on different tube heights, preventing sample evaporation during high-temperature cycles.
